Which subclasses of immunoglobulin G are found in rabbit serum?

Which classes of immunoglobulin G are found in rabbit serum?

In rabbit serum we will find four immunoglobulin isotypes, namely IgA, IgE, IgG and IgM. However, unlike other mammals, rabbits have only one subclass of IgG. Rabbit IgG is the most abundant immunoglobulin, and constitutes about 75% of the total rabbit serum immunoglobulins, with a concentration from 10-20 mg/ml. 

Other species have four IgG isotypes (subclasses).

Mouse: IgG1, IgG2a, IgG2b and IgG3,

Human: IgG1, IgG2, IgG3 and IgG4

IgG1 is the most abundant subclass in mouse and human serum. There is a difference in function of specific IgG subclasses.

Agrisera provides high-titer secondary antibodies to rabbit IgG:

Unconjugated | ALP-conjugated | HRP-conjugated | Biotinylated | Labelled with a fluorescent dye		  IgG molecule scheme

 Technical blog

Technical blog

Latest

Comparing antibodies between each other, why does it not work?
2024-11-25 How to remove cross-reactivity to Rubisco of a primary antibody?
2024-09-24 Which is an optimal buffer for protein extraction?
2024-07-29 Weak target protein bands and strong background at a top of a gel, what can be a reason for that?
2024-06-19 Why do some proteins always show as double bands on Western blot?
2024-05-30 How to further denature proteins transferred to PVDF membrane?
2024-05-22 Which isotype is a rabbit polyclonal antibody?
2024-05-06 Why bands on the blot are not distinct from each other?
2024-05-02 What parameters should be consider when transferring HMW proteins?
2024-03-01 Why some antibodies have a broad species reactivity, while the others do not?
2024-02-20

Archive


Close
Login / Retailer
Register
Forgot password?