Anti-RTA | Ricin toxic A chain
AS17 4143 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Ricinus communis
- Product Info
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Immunogen: Ricin A chain isolated from Ricinus communis var. Impala Host: Rabbit Clonality: Polyclonal Purity: Serum Format: Lyophilized Quantity: 50 µl Reconstitution: For reconstitution add 50 µl of sterile water Storage: Lyophilized antibody can be stored at -20°C for up to 3 years. Re-constituted antibody can be stored at 4°C for several days to weeks. Once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. Tested applications: ELISA (ELISA) Recommended dilution: 1: 10 000 (ELISA)
- Reactivity
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Confirmed reactivity: Ricinus communis Not reactive in: No confirmed exceptions from predicted reactivity are currently known - Additional Information
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Additional information (application): Antibody is recognizing active toxin complex containing both, ricin A and B subunits - Background
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Background: Ricin is a naturally occuring protein found in castor bean (Ricinus communis) acting as protein synthesis inhibitor. It is a toxin involved in plant defence. A chain of ricin can inactivate few thousands of ribosomes per minute. B chain facilitates the entry of A chain into the cell. Both protein chains, A and B must be present in order to produce an active toxin.
Ricin toxic A chain is an N-glycosylated heterodimer of approximately 60 to 65 kDa. - Reviews:
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